Monday, March 9, 2026
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Knee Arthritis Treatments Ranked



I rank the best injections for knee arthritis including platelet rich plasma (PRP), hyaluronic acid (HA / viscosupplementation), corticosteroids / cortisone, and stem cells such as bone marrow aspirate concentrate (BMAC) and adipose derived cells (MFAT).

► Things my patients have found helpful:
I get a lot of questions about what equipment is ‘best’ for treating a variety of conditions. The following is not meant to be an exhaustive or definitive list. If you have questions, please discuss with your healthcare provider. I have personally tried a number of the products below, but not all. I have included some based on positive feedback from my patients. As an Amazon Associate, Dr Peng earns from qualifying purchases. If you purchase any product using the below affiliate links, you are helping Dr Peng maintain this channel.

*Supplements*
The following are Thorne supplements which are NSF certified. NSF certifies that what’s on the label is in the bottle. They also do toxicology review to ensure the product contains no undeclared ingredients or unacceptable levels of contaminants.

Boswellia Extract:
Turmeric & Curcumin: ​​
Glucosamine & Chondroitin:
Creatine Monohydrate:
Whey Protein:
Omega 3 and 6:
Vitamin D 5000:
Vitamin B complex:
Magnesium Citrate/Malate:
Magnesium Glycinate:

*Soft Tissue & Rehab*
Theragun:
Massage ball:
Foam roller:
Stretching strap:
TENS unit:
Heating pad:
Heating patch:
Resistance bands:
Red light therapy:

*Braces & Supports*
Hinged knee brace:
Neoprene knee sleeve:
Volar wrist brace:
Thumb spica brace:
Ankle lace up brace:
Tennis/Golfer’s elbow brace:
Superfeet orthotic inserts:

*Other Resources*
Trigger Point Wall Posters:
The Trigger Point Manual:

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► ABOUT ME

Jeffrey Peng MD is a nonoperative orthopedist and sports medicine specialist. He focuses on maximizing non-surgical treatments for sports injuries and orthopedic conditions. He specializes in using orthobiologics and ultrasound guided minimally invasive techniques to treat osteoarthritis, tendinopathies, and musculoskeletal disorders.

Dr. Peng is board certified in sports medicine and family medicine. He completed residency with the Stanford family medicine residency program and completed his sports medicine training with the Stanford primary care sports medicine fellowship in San Jose. He is an active faculty member for both programs and is excited about training the next generation of physicians.

Dr. Peng’s sports medicine clinic is located in Campbell, California.
Twitter: @JeffreyPengMD;
Website:

► Disclaimer

My content reflects my own opinion and does not represent the views or opinions of my employers or hospital systems I am affiliated with. They are meant for educational purposes only. They do not substitute for the medical advice of a physician. Always seek the advice of your physician with any questions you may have regarding your health.

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26 COMMENTS

  1. I got degenerative meniscus root tear. I am 55 years old and a doctor recommended me to have a meniscus repair surgery. I have no pain now except when I walk around or stand for a while I have a stiffness and tightness around my knee. If I’m wearing knee brace I’m doing OK. Doctor, please advise me if the surgery is a must to do option since my doctor said that I have a high risk of osteoarthritis if I don’t do this kind of surgery early. He also mentioned that after 10 years I will have a knee replacement if I don’t do this. Are there any options that could improve my walking with less stiffness? For example a serious therapy can I go to see you for advice?

  2. Quack! Best Best Absolutely 1 shot instantly relief !!! No side effects! Enbrel will be the best!
    Try reading , Stop Following the FDA the government can’t even run a post office!!! TNF blockers work!!! I’ve done it

  3. Why have you not covered ARTHOSAMID which my Ortho Doctor is now pushing strongly over hyaluronic or PRP? Every resource that I have checked have suggested that it is much better than hyaluronic or PRP. Problem of course is cost.

  4. Thank you Dr. Peng for your excellent analysis. Here is my experience with PRP: I am a recently retired pharmacist, who had MCL surgery on my right knee from many years of going running and jogging. Some arthritis has set in. I have has 7 PRP injections on my knee so far over the past 2 years. Overall this has been a good benefit. I rate that it has helped "Some". The injections are performed by a good skillful surgeon in her office, using an ultrasound machine to help guide the injections. Few side effects. Also note max. of 7ml concentrated PRP injection to be used. Once I received 10ml and caused much more pain and stiffness for about 3 weeks. I also have received 2 injections of PRP for my shoulder, which has also helped. Notes: 1. It is necessary to receive a booster shot about evey 4 to 5 months, to keep the benefit effect up. 2. PRP therapy is expensive: $750 to $950 per each treatment, not covered by insurance. 3. Overall it appears to slow down the osteoarthritis, increase the quality of living ability. 4. Need to do stretching exercises each day (must). So is it worth it…? I says "Yes". Hope this helps.

  5. Bye the way IOVERA can be used to perform the PENG block which I don’t believe was named after you. The PENG procedure will relieve pain in the patient’s hip without an injection and without cortisone!!

  6. Hmm, I've been to China(Shenzhen) twice for umbilical stem cells, no problems, but also not sure if they worked. It might have been just my Carnivore diet, but the pain is totally gone now…

  7. There seem to be more conversations about glp-1 drugs such as Ozempic/Wegovy providing pain relief (beyond the benefits from simple weight loss.) Have you found this to be your anecdotal experience?

  8. Hello Dr. Peng, Thank you for the excellent presentation of the available injections today. Just curious, what do you think about the nSTRIDE injection…also called APS I think? Does this give good results for osteoarthritis of the knee? Is it similar to PRP? Thank you for your advice in advice. All the best. Jim

  9. I've done several PRP treatments on my knee (mild arthritis and a degenerative meniscus tear). The treatment last about 3-4 months and then the symptoms slowly return. I somehow manage to afford (employed) it but dread the day when that is no longer possible (retired). That said, PRP so far has not help with a rotator cuff tear. Going on week six with thus far little improvement. I am reading that 4-6 weeks is the point where most folks stat to get relief. Going for a follow-up treatment at the end of the month. None of this is cheap, which is BS because it really does help and if it were covered by insurance the price would likely come down and a whole lot of very expensive surgeries could be avoided.

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