Hyaluronic Acid Injections for Knee Arthritis: What Does Research Tell Us? #shorts
Living with knee osteoarthritis can be challenging, with pain impacting your mobility and quality of life. While many treatment options exist, hyaluronic acid (HA) injections have emerged as a widely discussed option for managing knee arthritis pain. But what does recent research tell us about their effectiveness?
Hyaluronic acid occurs naturally in your synovial fluid, providing lubrication and shock absorption in your joints. As knee osteoarthritis progresses, both the quantity and quality of this natural HA decreases, leading to increased pain and joint degradation.
Recent systematic reviews have revealed important distinctions between different HA products. High molecular weight (HMW) HA appears to provide greater pain relief compared to low molecular weight options, potentially surpassing the minimal clinically important difference threshold. This means patients may actually feel a meaningful difference in their pain levels with these specific formulations.
However, not all research findings are positive. A 2022 BMJ meta-analysis examining 169 trials found that viscosupplementation leads to only a small reduction in knee pain compared to placebo—a difference potentially too small to be clinically meaningful. More concerning, this analysis found a 49% higher risk of serious adverse events compared to placebo injections.
The molecular weight of the HA product matters significantly. Research shows HMW HA demonstrates:
Better binding to CD44 receptors
Greater reduction of inflammatory markers like IL-1β
Superior chondroprotective effects
Improved rheological properties similar to healthy joint fluid
For optimal results, evidence suggests treatments work best when:
Used in early to moderate stages of knee OA
Administered as part of a comprehensive treatment plan
Selected based on specific product characteristics rather than viewing all HA injections as equivalent
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Before considering this treatment, consult with your healthcare provider about whether HA injections might be appropriate for your specific condition, and which type might offer the best risk-benefit profile for your situation.
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What has been your experience with managing knee arthritis pain? Have you tried hyaluronic acid injections? Share your thoughts below!
#KneeArthritis #OsteoarthritisTreatment #HyaluronicAcid
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In the operating room, I get to perform more than 600 hip & knee replacement surgeries each year. From LIVE surgical demos to viral video highlights, together let’s explore – react – discuss all things related to bone and joint health
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Opinions expressed are solely my own and do not express the views or opinions of my employer. Information in this video is not intended or implied to be a substitute for professional medical advice, diagnosis and/or treatment. All content [images, digital graphics, text, and other information] contained in this video is for general information purposes only and does not replace or substitute for a consultation with a qualified physician or health professional.
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It is weird that why they can’t develop a type of gel that can last longer?
Mine worked for 2 years
Can these injections be injected into the upper back / trapezius muscles + muscles around shoulder joint ? I have pains in upper left traps which radiates to my shoulder / axilla / pecs and clavicle.
With AT Complex, I feel more active and energetic. No more joint pain controlling my life.
What about doing it in combination with PRP injection?
My family doctor injected me with hyaluronic acid and nothing happened. I waited for 24 hours and the pain got worse ‼️. Could it be that he injected the acid from the wrong angle? My inner knee that was hurting but he injected the acid from the outer knee. I think getting the right doctor doing the job is very important otherwise it is a waste of money and time . I had bad experience with PRP and Hyaluronic acid injection – expensive and doesn’t work a bit. Hurting my wallet 😢😢
Planet Ayurveda Joint Aid Plus reduced my inflammation naturally without harming my stomach.
I need this sh. How do i get it oit of the rooster and into my knee. Anybody?
Hello, Doctor! Can the injections be given on the finger joints?
Thanks for the quick and honest answer
good video
I truly appreciate your honesty and candor with these shorts. You are doing a real service.
What happen if u have pain again after 6 month
Please I need it
آقای دکتر برای ستون فقرات که مهرهای 5و4تحت فشارشدن ونخاع را فشارآوردن پای چپم از زانو به پایین خیلی کم لاغربنظرمیادوانگشتان پای چپ کمی بی حس شدن ونمیشه انگشتام بالا بیان . ممنون میشم ومدیونتون میشم راهنمایی کنید اگر میشه جراحی گردواگرشمادکترعزیز اگرصلاح میدونین بیام اونجا شمازخمت قبول کنین عمل انجام بدین با احترام از ایران 53سال دارم ❤❤❤❤❤
سلام دکتر این روش برای دیسک کمر اعصاب سیاتیک مهره احتمالا 5یا4باشه که نخاع را تحت فشار است وزده پای چپ اعصاب پای چپ کمی ضعیف شده راهی هست درمان بشه یاعمل جراحی بشه بتونم راحت راه برم ممنون میشم از راهنماییتون از ایران خدمتتون پیام دادم ❤❤
I need this soooooo
I wonder what a vegans take is on this? They had to unalive a rooster for that juice.
Aqui no Brasil 🇧🇷 virou “epidemia”! Muito importante usar com alto peso molecular associado á triancinolona e explicar que dá alívio mas não muda a evolução natural da artrose ! Uma ótima opção para aqueles pacientes que ainda resistem a cirurgia ptj mas sofrem por dor !👏🏼👏🏼👏🏼
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Lasted me for 6 months for 4 yrs, gave me time to get other activities out of the way.
That jell shit doesn't work. Save your money 💰 😊
Hi Doc.. worked well the first time for a year.. second time two weeks. It was time for the knee replacement. Thanks for the great videos.🇨🇦
☝️☝️☝️☝️ i hope that this is thrue
I can tell you hip injections only lasted a week. Not worth the pain. I heard they are more effective in the knee.
Bet if feels better than steroid shots lol
Any sources you can recommend to learn more about gel injection in the knee?
How many injections can you get before knee replacement is recommended?
That looks very helpful but just one problem… injections in the knee scare the crap out of me and it seems like it would hurt
Does this affect popping a joint? Like do/would they interfere?